The successful design of HIV protease inhibitors, Saquinavir, Indinavir and other important medicinal agents, initiated interest of researchers in structure based drug design approaches (SBDD).

In silico tools have indeed reframed the steps involved in traditional drug discovery and development process and the term in silico has become a familiar term in pharmaceutical sector like the terms in vitro and in vivo. In this article, the role of imidazolium zwitterionic molten salts as an organocatalyst for selective organic transformations including syn -selective aza-Henry reaction, Erlenmeyer reaction, synthesis of different heterocycles and their functionalization and regioselective ring-opening reactions has been elaborated chronically which will definitely be helping to the readers to explore this new class of organocatalyst for further applications. Moreover, by changing the cations and/or anions, the properties of ILs can be tuned in many ways. It has also been evident that C2вЂ“H of the imidazole has a vital role in catalyzing the reaction via electrophilic activation. Most importantly, these ionic-liquid catalysts are easily recyclable and subsequently reusable for multiple times without loss of significant catalytic efficiency. Imidazole-based zwitterionic-type molten salts are a new type of organocatalysts with high catalytic application in various organic transformations with added advantage of room temperature ionic liquid (RTIL) property. Returning to the rendering we have here, this is a brilliant way to play the supercar spec game, but those of you who prefer more colored approaches should check out the Ayrton Senna livery render.An environmentally benign, stable yet efficient organocatalyst is highly desirable from the viewpoint of green chemistry and catalysis. McLaren's designers went to extremes by cutting open the 'shrink-wrapped' body to reduce weight visually and functionally while recognizably a McLaren in proportional terms, you cannot follow a single line from the front to the rear without it passing through a functional air intake or vent,' the carmaker states. 'Viewed from above, the body is nature's most efficient shape - a teardrop - with body components 'clipped' onto the cabin to deliver optimal aerodynamic performance. Speaking of the Senna, the carbon fiber tub of the brute is complemented by carbon panels, with this making it the lightest Macca since the F1 (the thing tips the scales at 1,198 kg).ДЄnd if you're curious about how the British automotive producer describes the Senna, you might want to check out the paragraph below. Oh and there was also the rather strange pixel play delivering the wingless version of the 800 hp machine. Nevertheless, we wouldn't mind a cleaner approach and this render brings it without interfering with the design, as, for instance, was the case with the pixel play that brought us the shortnose version of the car. Don't get us wrong, we belong to the camp who approves of the overly complex styling of the hypercar, simply thanks to the aero-dictated path. You see, the main reason for which we adore this spec is the fact that it balances the appearance of the Senna. In fact, the only splashes of color on the car come front the inner sides of the air intakes sitting under the daytime running lights and the seatbelts, with both being finished in a striking shade of blue.

The pixel play we have here portrays the Woking animal in bare carbon form, while using black as the dominant cabin hue. And we've brought along a rendering that shows what might be the most delicious spec we've seen so far.

Thea render carbon fiber